Pharmacomechanical Catheter-Directed Thrombolysis for Deep-Vein Thrombosis

The post-thrombotic syndrome frequently develops in patients with proximal deep-vein thrombosis despite treatment with anticoagulant therapy. Pharmacomechanical catheter-directed thrombolysis (hereafter "pharmacomechanical thrombolysis") rapidly removes thrombus and is hypothesized to reduce the risk of the post-thrombotic syndrome.We randomly assigned 692 patients with acute proximal deep-vein thrombosis to receive either anticoagulation alone...