Development of polyvinylpyrrolidone/paclitaxel self-assemblies for breast cancer
Abstract
The goal of this investigation was to develop and demonstrate a polymer/paclitaxel self-assembly (PTX-SA) formulation. Polymer/PTX-SAs were screened based on smaller size of formulation using dynamic light scattering analysis. Additionally, fluorescence microscopy and flow cytometry studies exhibited that polyvinylpyrrolidone (PVP)-based PTX-SAs (PVP/PTX-SAs) had superior cellular internalization capability in MCF7 and MDA-MB-231 breast cancer...
Paper Details
Title
Development of polyvinylpyrrolidone/paclitaxel self-assemblies for breast cancer
Published Date
Jul 1, 2018
Journal
Volume
8
Issue
4
Pages
602 - 614
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