Functionalization of PCL-3D electrospun nanofibrous scaffolds for improved BMP2-induced bone formation
Abstract
Bone morphogenic protein 2 (BMP2) is a key growth factor for bone regeneration, possessing FDA approval for orthopedic applications. BMP2 is often required in supratherapeutic doses clinically, yielding adverse side effects and substantial treatment costs. Considering the crucial role of materials for BMPs delivery and cell osteogenic differentiation, we devote to engineering an innovative bone-matrix mimicking niche to improve low dose of...
Paper Details
Title
Functionalization of PCL-3D electrospun nanofibrous scaffolds for improved BMP2-induced bone formation
Published Date
Mar 1, 2018
Journal
Volume
10
Pages
194 - 202
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