Metal ion-improved complexation countercurrent chromatography for enantioseparation of dihydroflavone enantiomers
Abstract
Cu(II) ion was selected as an additive to improve the enantioseparation efficiency of three dihydroflavone enantiomers in high-speed counter-current chromatography (HSCCC), using hydroxypropyl-β-cyclodextrin (HP-β-CyD) as the chiral selector. The influences of important parameters, including the metal ion, the concentrations of HP-β-CyD and the Cu(II) ion, and the sample size were investigated. Under optimal conditions, three dihydroflavone...
Paper Details
Title
Metal ion-improved complexation countercurrent chromatography for enantioseparation of dihydroflavone enantiomers
Published Date
Jan 1, 2018
Journal
Volume
1532
Pages
1 - 9
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