Evaluation of immune-mediated idiosyncratic drug toxicity using chimeric HLA transgenic mice
Abstract
Immune-mediated idiosyncratic drug toxicity (IDT) is a rare adverse drug reaction, potentially resulting in death. Although genome-wide association studies suggest that the occurrence of immune-mediated IDT is strongly associated with specific human leukocyte antigen (HLA) allotypes, these associations have not yet been prospectively demonstrated. In this study, we focused on HLA-B*57:01 and abacavir (ABC)-induced immune-mediated IDT, and...
Paper Details
Title
Evaluation of immune-mediated idiosyncratic drug toxicity using chimeric HLA transgenic mice
Published Date
Nov 17, 2017
Journal
Volume
92
Issue
3
Pages
1177 - 1188
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History