Antiseptics for burns (Protocol)

Published on Jan 1, 2015in Cochrane Database of Systematic Reviews9.289
· DOI :10.1002/14651858.CD011821
Jo C Dumville58
Estimated H-index: 58
,
Devi Prasad Mohapatra7
Estimated H-index: 7
+ 2 AuthorsJanice Christie10
Estimated H-index: 10
Source
Abstract
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References37
Newest
#1Michael Peck (UA: University of Arizona)H-Index: 20
#2Melissa A. Pressman (UA: University of Arizona)H-Index: 4
Abstract Introduction Over 95% of burn deaths occur in low- and middle-income countries globally. However, the association between burn mortality rates and economic health has not been evaluated for individual countries. This study seeks to answer the question, how strong is the correlation between burn mortality and national indices of economic strength? Methods A retrospective review was performed for 189 countries during 2008–2010 using economic data from the World Bank as well as mortality d...
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#1Evangelos Kontopantelis (University of Manchester)H-Index: 57
#2David A. Springate (University of Manchester)H-Index: 17
Last. David Reeves (University of Manchester)H-Index: 68
view all 3 authors...
Background Heterogeneity has a key role in meta-analysis methods and can greatly affect conclusions. However, true levels of heterogeneity are unknown and often researchers assume homogeneity. We aim to: a) investigate the prevalence of unobserved heterogeneity and the validity of the assumption of homogeneity; b) assess the performance of various meta-analysis methods; c) apply the findings to published meta-analyses. Methods and Findings We accessed 57,397 meta-analyses, available in the Cochr...
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#2Jesús López-Alcalde (Cochrane Collaboration)H-Index: 8
Last. Xavier Bonfill Cosp (Autonomous University of Barcelona)H-Index: 20
view all 5 authors...
Background Infection of burn wounds is a serious problem because it can delay healing, increase scarring and invasive infection may result in the death of the patient. Antibiotic prophylaxis is one of several interventions that may prevent burn wound infection and protect the burned patient from invasive infections. Objectives To assess the effects of antibiotic prophylaxis on rates of burn wound infection. Search methods In January 2013 we searched the Wounds Group Specialised Register; The Coc...
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#1Jason Wasiak (Monash University)H-Index: 41
#2Heather Cleland (Alfred Hospital)H-Index: 33
Last. Anneliese Spinks (Griffith University)H-Index: 32
view all 4 authors...
Background An acute burn wound is a complex and evolving injury. Extensive burns produce systemic consequences, in addition to local tissue damage. Treatment of partial thickness burn wounds is directed towards promoting healing and a wide variety of dressings are currently available. Improvements in technology and advances in understanding of wound healing have driven the development of new dressings. Dressing selection should be based on their effects on healing, but ease of application and re...
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#1Evangelos Kontopantelis (University of Manchester)H-Index: 57
#2David Reeves (University of Manchester)H-Index: 68
Meta-analysis (MA) is a statistical methodology that combines the results of several independent studies considered by the analyst to be ‘combinable’. The simplest approach, the fixed-effects (FE) model, assumes the true effect to be the same in all studies, while the random-effects (RE) family of models allows the true effect to vary across studies. However, all methods are only correct asymptotically, while some RE models assume that the true effects are normally distributed. In practice, MA m...
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#1Emine Alp (Erciyes University)H-Index: 31
#2Atilla Coruh (Erciyes University)H-Index: 12
Last. Mehmet Doganay (Erciyes University)H-Index: 28
view all 5 authors...
: To evaluate the risk factors for nosocomial infection (NI) and mortality in a university hospital, 10-year data of burn patients were assessed retrospectively. The study was conducted at Erciyes University's Burn Center during 2000 and 2009. The records of 1190 patients were obtained. Overall, 131 (11%) patients had 206 NIs with an incidence density of 14.7 infections/1000 patient days. Burn wound infection (n = 109, 53%) was the most common NI. High (%TBSA burned) and late excision were found...
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#1Michael Peck (UA: University of Arizona)H-Index: 20
Abstract Globally in 2004, the incidence of burns severe enough to require medical attention was nearly 11 million people and ranked fourth in all injuries, higher than the combined incidence of tuberculosis and HIV infections. Fortunately, although burns and fires account for over 300,000 deaths each year throughout the world, the vast majority of burns are not fatal. Nonetheless, fire-related burns are also among the leading causes of disability-adjusted life years (DALYs) lost in low- and mid...
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#1Edward F. Keen (San Antonio Military Medical Center)H-Index: 6
#2Brian J. Robinson (San Antonio Military Medical Center)H-Index: 5
Last. Clinton K. Murray (USU: Uniformed Services University of the Health Sciences)H-Index: 69
view all 7 authors...
Abstract Infections caused by multidrug-resistant (MDR) pathogens are associated with significant morbidity and mortality in patients with burn injuries. We performed a 6-year antibiotic susceptibility records review from January 2003 to December 2008 to assess the prevalence of MDR isolates by pathogen at the US Army Institute of Surgical Research Burn Center. During the study period Acinetobacter baumannii (780 isolates [22%]) was the most prevalent organism recovered, followed by Pseudomonas ...
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#1Marja N. Storm-Versloot (UvA: University of Amsterdam)H-Index: 11
#2Cornelis G Vos (UvA: University of Amsterdam)H-Index: 1
Last. Hester Vermeulen (UvA: University of Amsterdam)H-Index: 33
view all 4 authors...
Background Silver-containing treatments are popular and used in wound treatments to combat a broad spectrum of pathogens, but evidence of their effectiveness in preventing wound infection or promoting healing is lacking. Objectives To establish the effects of silver-containing wound dressings and topical agents in preventing wound infection and healing of wounds. Search methods We searched the Cochrane Wounds Group Specialised Register (6 May 2009); The Cochrane Central Register of Controlled Tr...
Source
#1Tomer Avni (Rabin Medical Center)H-Index: 22
#2Ariela LevcovichH-Index: 2
Last. Mical PaulH-Index: 34
view all 5 authors...
Objective To assess the evidence for prophylactic treatment with systemic antibiotics in burns patients. Design Systematic review and meta-analysis of randomised or quasi-randomised controlled trials recruiting burns inpatients that compared antibiotic prophylaxis (systemic, non-absorbable, or topical) with placebo or no treatment. Data sources PubMed, Cochrane Library, LILACS, Embase, conference proceedings, and bibliographies. No language, date, or publication status restrictions were imposed....
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Cited By2
Newest
#1Mehul Thakkar (Southmead Hospital)H-Index: 2
#2Christopher Wearn (Southmead Hospital)H-Index: 1
Last. Catalina Estela (Southmead Hospital)H-Index: 1
view all 6 authors...
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#1Zhenmi Liu (MAHSC: Manchester Academic Health Science Centre)H-Index: 12
#2Jo C Dumville (University of Manchester)H-Index: 58
Last. Hung-Yuan Cheng (UoB: University of Bristol)H-Index: 8
view all 13 authors...
This is a protocol for a Cochrane Review (Overview). The objectives are as follows: To present an overview of the effectiveness and safety of interventions delivered during the intra-operative period aimed at preventing surgical site infections in all populations under going surgery in operating theatre settings.
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