Regulation of the epithelial barrier by post-translational modifications of tight junction membrane proteins
Abstract
Body and organ surfaces in multicellular organisms are covered with a sheet of epithelial cells. The tight junction (TJ) is an adhesive structure that seals the gap between epithelial cells and functions as a selective barrier to prevent the entry of antigens and pathogenic microbes from the extracellular environment. Several transmembrane proteins that constitute the TJ (claudin, occludin, tricellulin and angulin) have been identified. As...
Paper Details
Title
Regulation of the epithelial barrier by post-translational modifications of tight junction membrane proteins
Published Date
Nov 24, 2017
Journal
Volume
163
Issue
4
Pages
265 - 272
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