GATA3 Regulates the Development and Functions of Innate Lymphoid Cell Subsets at Multiple Stages

Innate lymphoid cells (ILCs) are regarded as the innate counterpart of effector CD4 T helper (Th) cells. Just as Th cells, ILCs are classified into distinct subsets based on their functions that are delivered mainly through effector cytokine production. Both ILCs and Th cells play critical roles in a variety of protective immune responses and inflammation diseases. Similar to Th cell differentiation, the development of ILC subsets depends on...