PRDM14 directly interacts with heat shock proteins HSP90α and glucose-regulated protein 78

PRDM 14 is overexpressed in various cancers and can regulate cancer phenotype under certain conditions. Inhibiting PRDM 14 expression in breast and pancreatic cancers has been reported to reduce cancer stem‐like phenotypes, which are associated with aggressive tumor properties. Therefore, PRDM 14 is considered a promising target for cancer therapy. To develop a pharmaceutical treatment, the mechanism and interacting partners of PRDM 14 need to...