Original paper

Closed-loop control of targeted ultrasound drug delivery across the blood–brain/tumor barriers in a rat glioma model

Volume: 114, Issue: 48
Published: Nov 13, 2017
Abstract
Cavitation-facilitated microbubble-mediated focused ultrasound therapy is a promising method of drug delivery across the blood-brain barrier (BBB) for treating many neurological disorders. Unlike ultrasound thermal therapies, during which magnetic resonance thermometry can serve as a reliable treatment control modality, real-time control of modulated BBB disruption with undetectable vascular damage remains a challenge. Here a closed-loop...
Paper Details
Title
Closed-loop control of targeted ultrasound drug delivery across the blood–brain/tumor barriers in a rat glioma model
Published Date
Nov 13, 2017
Volume
114
Issue
48
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