Therapeutic dose of green tea extract provokes liver damage and exacerbates paracetamol-induced hepatotoxicity in rats through oxidative stress and caspase 3-dependent apoptosis
Abstract
Green tea extract (GTE) is considered to be endowed with countless healthful properties. Nevertheless, data concerning the hepatoprotective activities of GTE and its utilization as a therapeutic intervention for paracetamol (APAP) overdose are conflicting and intriguing. The present study was undertaken to address the effect of therapeutic dose of GTE on the liver, evaluate the potential hepatoprotection of GTE against APAP-induced...
Paper Details
Title
Therapeutic dose of green tea extract provokes liver damage and exacerbates paracetamol-induced hepatotoxicity in rats through oxidative stress and caspase 3-dependent apoptosis
Published Date
Dec 1, 2017
Volume
96
Pages
798 - 811
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