Tau PET imaging predicts cognition in atypical variants of Alzheimer's disease

Accumulation of paired helical filament tau contributes to neurodegeneration in Alzheimer's disease (AD). 18 F‐flortaucipir is a positron emission tomography (PET) radioligand sensitive to tau in AD, but its clinical utility will depend in part on its ability to predict cognitive symptoms in diverse dementia phenotypes associated with selective, regional uptake. We examined associations between 18 F‐flortaucipir and cognition in 14...