Resveratrol Exerts Antioxidant Effects by Activating SIRT2 To Deacetylate Prx1
Abstract
Resveratrol is a promising chemical agent that treats multiple aging-related diseases and improves life span. While reactive oxygen species undoubtedly play ubiquitous roles in the aging process and resveratrol has been shown to be an effective antioxidant, the mechanism through which resveratrol acts against oxidative stress remains unknown. Here we show that resveratrol activates SIRT2 to deacetylate Prx1, leading to an increased H2O2...
Paper Details
Title
Resveratrol Exerts Antioxidant Effects by Activating SIRT2 To Deacetylate Prx1
Published Date
Nov 16, 2017
Journal
Volume
56
Issue
48
Pages
6325 - 6328
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