Discovery of a novel subset of lung resident macrophages that regulate pathogen clearance and immune homeostasis after respiratory infection
Abstract
The importance of tissue resident macrophages (TRMϕ) for pathogen clearance and homeostasis is beginning to emerge. However, our understanding of the multifaceted roles these macrophages play in mucosal tissues such as the lung remains incomplete. Currently the major population of TRMϕs in the lung is known to be alveolar macrophages (AMϕ) that express CD11c and CD169. Here we report a novel subset of CD169+ lung resident macrophages that are...
Paper Details
Title
Discovery of a novel subset of lung resident macrophages that regulate pathogen clearance and immune homeostasis after respiratory infection
Published Date
May 1, 2016
Journal
Volume
196
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