Leveraging genome characteristics to improve gene discovery for putamen subcortical brain structure
Abstract
Discovering genetic variants associated with human brain structures is an on-going effort. The ENIGMA consortium conducted genome-wide association studies (GWAS) with standard multi-study analytical methodology and identified several significant single nucleotide polymorphisms (SNPs). Here we employ a novel analytical approach that incorporates functional genome annotations (e.g., exon or 5′UTR), total linkage disequilibrium (LD) scores and...
Paper Details
Title
Leveraging genome characteristics to improve gene discovery for putamen subcortical brain structure
Published Date
Nov 16, 2017
Journal
Volume
7
Issue
1
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