The role of hydrophobic modification on hyaluronic acid dynamics and self-assembly
Abstract
The advent of nanomedicine has rejuvenated the need for increased understanding of the fundamental physicochemical properties of polymeric amphiphiles. Hyaluronic acid (HA) is a hydrophilic polysaccharide that is frequently conjugated to hydrophobic moieties and then used to entrap dyes and therapeutics. Here, we develop computational models to examine the effects of the hydrophobic modification on supramolecular behavior among three...
Paper Details
Title
The role of hydrophobic modification on hyaluronic acid dynamics and self-assembly
Published Date
Feb 1, 2018
Journal
Volume
182
Pages
132 - 141
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