The Growing Role of Electron Microscopy in Anti-parasitic Drug Discovery
Abstract
Background: Parasite diseases are a huge burden on human health causing significant morbidity and mortality. However, parasite structure based drug discovery programmes have been hindered by a lack of high resolution structural information from parasite derived proteins and have often relied upon homology models from mammalian systems. The recent renaissance in electron microscopy (EM) has caused a dramatic rise in the number of structures being...
Paper Details
Title
The Growing Role of Electron Microscopy in Anti-parasitic Drug Discovery
Published Date
Jan 17, 2019
Journal
Volume
25
Issue
39
Pages
5279 - 5290
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