Neurophagy, the phagocytosis of live neurons and synapses by glia, contributes to brain development and disease.
Abstract
It was previously thought that neurons were phagocytosed only when dead or dying. However, it is increasingly clear that viable synapses, dendrites, axons and whole neurons can be phagocytosed alive (defined here as neurophagy), and this may contribute to a wide range of developmental, physiological and pathological processes. Phagocytosis of live synapses, dendrites and axons by glia contributes to experience-dependent sculpting of neuronal...
Paper Details
Title
Neurophagy, the phagocytosis of live neurons and synapses by glia, contributes to brain development and disease.
Published Date
Oct 1, 2018
Journal
Volume
285
Issue
19
Pages
3566 - 3575
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