Commensal Lactobacillus Controls Immune Tolerance during Acute Liver Injury in Mice
Abstract
•During acute liver injury, commensal Lactobacillus species accumulates in the gut•Lactobacillus activates IL-22 production by gut innate lymphoid cells•Gut-derived IL-22 contributes to the induction of liver tolerance Gut-derived microbial antigens trigger the innate immune system during acute liver injury. During recovery, regulatory immunity plays a role in suppressing inflammation; however, the precise mechanism underlying this process...
Paper Details
Title
Commensal Lactobacillus Controls Immune Tolerance during Acute Liver Injury in Mice
Published Date
Oct 1, 2017
Journal
Volume
21
Issue
5
Pages
1215 - 1226
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