The DNA methyltransferase family: a versatile toolkit for epigenetic regulation
Abstract
The DNA methyltransferase (DNMT) family comprises a conserved set of DNA-modifying enzymes that have a central role in epigenetic gene regulation. Recent studies have shown that the functions of the canonical DNMT enzymes - DNMT1, DNMT3A and DNMT3B - go beyond their traditional roles of establishing and maintaining DNA methylation patterns. This Review analyses how molecular interactions and changes in gene copy numbers modulate the activity of...
Paper Details
Title
The DNA methyltransferase family: a versatile toolkit for epigenetic regulation
Published Date
Oct 16, 2017
Journal
Volume
19
Issue
2
Pages
81 - 92
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