Leaders in collective migration: are front cells really endowed with a particular set of skills?

Eric Theveneau; Claudia Linker

doi:https://doi.org/10.12688/f1000research.11889.1

doi.org/10.12688/f1000research.11889.1

Leaders in collective migration: are front cells really endowed with a particular set of skills?

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Volume: 6, Pages: 1899 - 1899

Published: Oct 27, 2017

Abstract

Collective cell migration is the coordinated movement emerging from the interaction of at least two cells. In multicellular organisms, collective cell migration is ubiquitous. During development, embryonic cells often travel in numbers, whereas in adults, epithelial cells close wounds collectively. There is often a division of labour and two categories of cells have been proposed: leaders and followers. These two terms imply that...