Clinical importance of IL-22 cascade in IBD
Abstract
IL-22 is a relatively new cytokine that is characterized by several unique biological properties. In the intestines, the effect of IL-22 is restricted mainly to non-lymphoid cells such as epithelial cells. Interestingly, the expression pattern and major cellular source of IL-22 have distinct difference between large and small intestines. IL-22 possesses an ability to constitutively activate STAT3 for promoting epithelial cell regeneration and...
Paper Details
Title
Clinical importance of IL-22 cascade in IBD
Published Date
Oct 26, 2017
Journal
Volume
53
Issue
4
Pages
465 - 474
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History