Alkaline phosphatase and cardiovascular disease

Alkaline phosphatase (AP) is a plasma membrane-anchored enzyme that is widely distributed in nature from bacteria to humans. AP has a broad specificity and catalyzes the hydrolysis of phosphate monoesters from a wide range of substrates. The best known physiological function of AP is participation in the bone mineralization by increasing the availability of phosphate that is used for hydroxyapatite synthesis. Measurement of AP activity in plasma...