Fibroblast growth factor 13 regulates glioma cell invasion and is important for bevacizumab-induced glioma invasion.

Published on Mar 23, 2018in Oncogene9.867
路 DOI :10.1038/ONC.2017.373
Yoshihiro Otani8
Estimated H-index: 8
(Okayama University),
Tomotsugu Ichikawa23
Estimated H-index: 23
(Okayama University)
+ 10 AuthorsIsao Date62
Estimated H-index: 62
(Okayama University)
Fibroblast growth factor 13 regulates glioma cell invasion and is important for bevacizumab-induced glioma invasion
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Platinum-based regimens are the most widely used chemotherapy regimens, but cancer cells often develop resistance, which impedes therapy outcome for patients. Previous studies have shown that fibroblast growth factor 13 (FGF13) is associated with resistance to platinum drugs in HeLa cells. However, the mechanism and universality of this effect have not been clarified. Here, we found that FGF13 was associated with poor platinum-based chemotherapy outcomes in a variety of cancers, such as lung, en...
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