Macromolecular assemblies of complex polysaccharides with galectin-3 and their synergistic effects on function

Volume: 474, Issue: 22, Pages: 3849 - 3868
Published: Nov 9, 2017
Abstract
Although pectin-derived polysaccharides can antagonize galectin function in various pathological disorders, the nature of their binding interactions needs to be better defined for developing them as drugs. Moreover, given their relatively large size and complexity, pectin-derived polysaccharides are also useful as model systems to assess inter-polysaccharide and protein–polysaccharide interactions. Here, we investigated interactions between...
Paper Details
Title
Macromolecular assemblies of complex polysaccharides with galectin-3 and their synergistic effects on function
Published Date
Nov 9, 2017
Volume
474
Issue
22
Pages
3849 - 3868
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