Combining actigraphy, ecological momentary assessment and neuroimaging to study apathy in patients with schizophrenia

Apathy can be defined as a reduction of goal-directed behavior and is a strong predictor for poor functional outcome in schizophrenia. However, no objective measure of apathy has been identified and assessment is limited to retrospective interview-based ratings. Here we aimed to identify more precise objective readouts of apathy for translational research and clinical practice. We employed a combined approach including interview-based ratings of...