Towards standards for human fecal sample processing in metagenomic studies
Abstract
Technical variation in metagenomic analysis must be minimized to confidently assess the contributions of microbiota to human health. Here we tested 21 representative DNA extraction protocols on the same fecal samples and quantified differences in observed microbial community composition. We compared them with differences due to library preparation and sample storage, which we contrasted with observed biological variation within the same specimen...
Paper Details
Title
Towards standards for human fecal sample processing in metagenomic studies
Published Date
Oct 2, 2017
Journal
Volume
35
Issue
11
Pages
1069 - 1076
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Notes
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