Body mass index is associated with cortical thinning with different patterns in mid- and late-life

High BMI at midlife is associated with increased risk of dementia as well as faster decline in cognitive function. In late-life, however, high BMI has been found to be associated with both increased and decreased dementia risk. The objective of this study was to investigate the neural substrates of this age-related change in body mass index (BMI) risk. We measured longitudinal cortical thinning over the whole brain, based on magnetic resonance...