Comparison of Endoscopic Ultrasound–Fine-Needle Aspiration and Endoscopic Ultrasound–Fine-Needle Biopsy for Solid Lesions in a Multicenter, Randomized Trial

Background & AimsEndoscopic ultrasound with fine-needle aspiration (FNA) is the standard of care for tissue sampling of solid lesions adjacent to the gastrointestinal tract. Fine-needle biopsy (FNB) may provide higher diagnostic yield with fewer needle passes. The aim of this study was to assess the difference in diagnostic yield between FNA and FNB.MethodsThis is a multicenter, prospective randomized clinical trial from 6 large tertiary care...