A Bidirectional Relationship Between Symptom Reporting and Perceived Stress, But Not Disease Activity, in Inflammatory Bowel Disease: More Questions Than Answers?

Sexton KA, Walker JR, Graff LA, et al. Evidence of bidirectional associations between perceived stress and symptom activity: a prospective longitudinal investigation in inflammatory bowel disease. Inflamm Bowel Dis. 2017;23:473–483. Psychological comorbidity including anxiety, depression, somatization, and perceived stress is prevalent in inflammatory bowel disease (IBD). Risk factors for the development of these disorders are thought to include...