Utility of Phox2b immunohistochemical stain in neural crest tumours and non‐neural crest tumours in paediatric patients

Aims This study evaluated the utility of Phox2b in paediatric tumours. Previously, tyrosine hydroxylase ( TH ) was the most widely utilised sympathoadrenal marker specific for neural crest tumours with neuronal/neuroendocrine differentiation. However, its sensitivity is insufficient. Recently Phox2b has emerged as another specific marker for this entity. Methods and results Phox2b immunohistochemistry ( IHC ) was performed on 159 paediatric...