Enhanced Bioactivity and Bacteriostasis of PEEK Polymers Through Incorporation of Silicon Nitride Particles

BACKGROUND CONTEXT: Appositional bone on- and through-growth are essential requirements for successful spinal arthrodesis using intervertebral spacers. In addition, perioperative or latent infections are frequent causes for revision surgeries, requiring the removal and replacement of infected implants. Biomaterials which promote osseointegration while minimizing the risk of infection are necessary for improved spinal fusion outcomes. Although...