Enriching the biological space of natural products and charting drug metabolites, through real time biotransformation monitoring: The NMR tube bioreactor
Volume: 1862, Issue: 1, Pages: 1 - 8
Published: Jan 1, 2018
Abstract
Natural products offer a wide range of biological activities, but they are not easily integrated in the drug discovery pipeline, because of their inherent scaffold intricacy and the associated complexity in their synthetic chemistry. Enzymes may be used to perform regioselective and stereoselective incorporation of functional groups in the natural product core, avoiding harsh reaction conditions, several protection/deprotection and purification...
Paper Details
Title
Enriching the biological space of natural products and charting drug metabolites, through real time biotransformation monitoring: The NMR tube bioreactor
Published Date
Jan 1, 2018
Volume
1862
Issue
1
Pages
1 - 8
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