Spike Frequency Adaptation in Neurons of the Central Nervous System
Abstract
Neuronal firing patterns and frequencies determine the nature of encoded information of the neurons. Here we discuss the molecular identity and cellular mechanisms of spike-frequency adaptation in central nervous system (CNS) neurons. Calcium-activated potassium (KCa) channels such as BKCa and SKCa channels have long been known to be important mediators of spike adaptation via generation of a large afterhyperpolarization when neurons are...
Paper Details
Title
Spike Frequency Adaptation in Neurons of the Central Nervous System
Published Date
Aug 31, 2017
Volume
26
Issue
4
Pages
179 - 185
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