Zinc chloride-induced TRPA1 activation does not contribute to toxicity in vitro

Volume: 293, Pages: 133 - 139
Published: Sep 1, 2018
Abstract
The hygroscopic zinc chloride (ZnCl2) is often used to generate smoke screens. Severe adverse pulmonary health effects have been associated with inhalation of ZnCl2 smokes. The underlying molecular toxicology is not known. Recent studies have shown that the Transient Receptor Potential Channel A1 (TRPA1) is important for sensing toxic chemicals. TRPA1 was shown to be activated by Zn2+ which was linked to pain and inflammation. In the present...
Paper Details
Title
Zinc chloride-induced TRPA1 activation does not contribute to toxicity in vitro
Published Date
Sep 1, 2018
Volume
293
Pages
133 - 139
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