Targeting Hypoxia to Improve Non-Small Cell Lung Cancer Outcome.

Volume: 110, Issue: 1, Pages: 14 - 30
Published: Jan 1, 2018
Abstract
Oxygen deprivation (hypoxia) in non-small cell lung cancer (NSCLC) is an important factor in treatment resistance and poor survival. Hypoxia is an attractive therapeutic target, particularly in the context of radiotherapy, which is delivered to more than half of NSCLC patients. However, NSCLC hypoxia-targeted therapy trials have not yet translated into patient benefit. Recently, early termination of promising evofosfamide and tarloxotinib...
Paper Details
Title
Targeting Hypoxia to Improve Non-Small Cell Lung Cancer Outcome.
Published Date
Jan 1, 2018
Volume
110
Issue
1
Pages
14 - 30
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