Decreasing CB1 receptor signaling in Kupffer cells improves insulin sensitivity in obese mice.

Volume: 6, Issue: 11, Pages: 1517 - 1528
Published: Nov 1, 2017
Abstract
null null Objective null Obesity-induced accumulation of ectopic fat in the liver is thought to contribute to the development of insulin resistance, and increased activity of hepatic CB1R has been shown to promote both processes. However, lipid accumulation in liver can be experimentally dissociated from insulin resistance under certain conditions, suggesting the involvement of additional mechanisms. Obesity is also associated with...
Paper Details
Title
Decreasing CB1 receptor signaling in Kupffer cells improves insulin sensitivity in obese mice.
Published Date
Nov 1, 2017
Volume
6
Issue
11
Pages
1517 - 1528
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