miR-625-3p is upregulated in CD8+ T cells during early immune reconstitution after allogeneic stem cell transplantation
Abstract
Alloreactive CD8+ T-cells mediate the curative graft-versus-leukaemia effect, the anti-viral immunity and graft-versus-host-disease (GvHD) after allogeneic stem cell transplantation (SCT). Thus, immune reconstitution with CD8+ T-cells is critical for the outcome of patients after allogeneic SCT. Certain miRNAs such as miR-146a or miR-155 play an important role in the regulation of post-transplant immunity in mice. While some miRNAs e.g. miR-423...
Paper Details
Title
miR-625-3p is upregulated in CD8+ T cells during early immune reconstitution after allogeneic stem cell transplantation
Published Date
Aug 30, 2017
Journal
Volume
12
Issue
8
Pages
e0183828 - e0183828
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