UCP2 and PRMT1 are key prognostic markers for lung carcinoma patients

Volume: 8, Issue: 46, Pages: 80278 - 80285
Published: Aug 28, 2017
Abstract
Cancer cells have developed unique strategies to meet their high energy demand. Therefore, they have established a setting of Ca2+-triggered high mitochondrial activity. But mitochondrial Ca2+ uptake has to be strictly controlled to avoid mitochondrial Ca2+ overload that would cause apoptotic cell death. Methylation by protein arginine methyl transferase 1 (PRMT1) desensitizes the mitochondrial Ca2+ uptake machinery and reduces mitochondrial...
Paper Details
Title
UCP2 and PRMT1 are key prognostic markers for lung carcinoma patients
Published Date
Aug 28, 2017
Journal
Volume
8
Issue
46
Pages
80278 - 80285
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