Gain insight into research trends and influential papers with Research Intelligence.
doi.org/10.1016/j.ccell.2017.07.007

Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

..., Richard A. Moore
66
Cancer Cell50.30
Volume: 32, Issue: 2, Pages: 185 - 203.e13
Published: Aug 1, 2017
Abstract
We performed integrated genomic, transcriptomic, and proteomic profiling of 150 pancreatic ductal adenocarcinoma (PDAC) specimens, including samples with characteristic low neoplastic cellularity. Deep whole-exome sequencing revealed recurrent somatic mutations in KRAS, TP53, CDKN2A, SMAD4, RNF43, ARID1A, TGFβR2, GNAS, RREB1, and PBRM1. KRAS wild-type tumors harbored alterations in other oncogenic drivers, including GNAS, BRAF, CTNNB1, and...
Paper Fields
Paper Details
Title
Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma
DOI
doi.org/10.1016/j.ccell.2017.07.007
Published Date
Aug 1, 2017
Journal
Cancer Cell
Volume
32
Issue
2
Pages
185 - 203.e13
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.