Immune characterization of the HBHA-specific response in Mycobacterium tuberculosis-infected patients with or without HIV infection
Abstract
RD1-based Interferon-γ Release Assays (IGRAs) cannot distinguish latent from active tuberculosis (TB) disease. Conversely, a positive response to heparin-binding haemagglutinin (HBHA)-based IGRAs, among TB-infected subjects, correlates with Mycobacterium tuberculosis (Mtb) containment and low risk of TB progression. The aim of this study was to characterize HBHA-immune responses in HIV-infected and uninfected subjects with active TB or latent TB...
Paper Details
Title
Immune characterization of the HBHA-specific response in Mycobacterium tuberculosis-infected patients with or without HIV infection
Published Date
Aug 24, 2017
Journal
Volume
12
Issue
8
Pages
e0183846 - e0183846
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