Modelling of microbial polyhydroxyalkanoate surface binding protein PhaP for rational mutagenesis

Summary Phasins are unusual amphiphilic proteins that bind to microbial polyhydroxyalkanoate ( PHA ) granules in nature and show great potential for various applications in biotechnology and medicine. Despite their remarkable diversity, only the crystal structure of Pha P A h from Aeromonas hydrophila has been solved to date. Based on the structure of Pha P A h , homology models of Pha P A z from Azotobacter sp . FA ‐8 and Pha P TD from...