A Metabolomics-Based Strategy for the Mechanism Exploration of Traditional Chinese Medicine:Descurainia sophiaSeeds Extract and Fractions as a Case Study

A UPLC-QTOF-MS based metabolomics research was conducted to explore potential biomarkers which would increase our understanding of the model and to assess the integral efficacy of Descurainia sophia seeds extract (DS-A). Additionally, DS-A was split into five fractions in descending order of polarity, which were utilized to illustrate the mechanism together. The 26 identified biomarkers were mainly related to disturbances in phenylalanine,...