Lipophagy maintains energy homeostasis in the kidney proximal tubule during prolonged starvation

Volume: 13, Issue: 10, Pages: 1629 - 1647
Published: Sep 8, 2017
Abstract
Macroautophagy/autophagy is a self-degradation process that combats starvation. Lipids are the main energy source in kidney proximal tubular cells (PTCs). During starvation, PTCs increase fatty acid (FA) uptake, form intracellular lipid droplets (LDs), and hydrolyze them for use. The involvement of autophagy in lipid metabolism in the kidney remains largely unknown. Here, we investigated the autophagy-mediated regulation of renal lipid...
Paper Details
Title
Lipophagy maintains energy homeostasis in the kidney proximal tubule during prolonged starvation
Published Date
Sep 8, 2017
Journal
Volume
13
Issue
10
Pages
1629 - 1647
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