MRTF transcription and Ezrin-dependent plasma membrane blebbing are required for entotic invasion
Abstract
Entosis is a nonapoptotic form of cell death initiated by actomyosin-dependent homotypic cell-in-cell invasion that can be observed in malignant exudates during tumor progression. We previously demonstrated formin-mediated actin dynamics at the rear of the invading cell as well as nonapoptotic plasma membrane (PM) blebbing in this cellular motile process. Although the contractile actin cortex involved in bleb-driven motility is well...
Paper Details
Title
MRTF transcription and Ezrin-dependent plasma membrane blebbing are required for entotic invasion
Published Date
Aug 3, 2017
Journal
Volume
216
Issue
10
Pages
3087 - 3095
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Notes
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