Self-healing and photoluminescent carboxymethyl cellulose-based hydrogels

Published on Sep 1, 2017in European Polymer Journal3.862
· DOI :10.1016/J.EURPOLYMJ.2017.06.008
Yong Mei Chen33
Estimated H-index: 33
(Xi'an Jiaotong University),
Lei Sun2
Estimated H-index: 2
(Xi'an Jiaotong University)
+ 4 AuthorsChen Hu4
Estimated H-index: 4
(Xi'an Jiaotong University)
Abstract Nature resource-derived hydrogels with the properties of both self-healing and photoluminescence are urgent needed to develop. Herein, we demonstrate that carboxymethyl cellulose (CMC)-based hydrogels can be engineered to exhibit the integrate capabilities of self-healing, photoluminescence and stretchability by a facile, green and economic approach. The CMC-based hydrogels present blue-green color under ultraviolet light, and self-heal in ambient temperature without any external stimulus with 95% healing efficiency. Moreover, the healed hydrogel can be stretched nearly 2.5 times of their original length. The stretchable self-healing and photoluminescent CMC-based hydrogels can adhere to glass, plastic and soft tissues. The vessel sealant for preventing the leakage of aqueous solution and prototype of mucoadhesive for stomach perforations are demonstrated. With these novel properties, the easy-to-synthesize, mass production, multifunctional smart CMC-based hydrogels hold great potential for applications in biomedical and engineering fields.
📖 Papers frequently viewed together
42 Citations
23 Citations
129 Citations
#1Wen Jiang Zheng (Xi'an Jiaotong University)H-Index: 7
#2Jie Gao (Xi'an Jiaotong University)H-Index: 2
Last. Yong Mei Chen (Xi'an Jiaotong University)H-Index: 33
view all 5 authors...
Abstract As a material derived from cellulose, which is abundant in nature, carboxymethyl cellulose (CMC) has been used as an ingredient to synthesize hydrogels for various applications. The introduction of self-healing properties in CMC hydrogels will expand their service life and scope of application. We report a facile way to fabricate CMC hydrogels with self-healing behaviour. The self-healing CMC hydrogel is achieved by acidifying the CMC paste in citric acid solution. The CMC hydrogel can ...
42 CitationsSource
#1Angelina Cayuela (UCO: University of Córdoba (Spain))H-Index: 11
#2Stuart R. Kennedy (Durham University)H-Index: 16
Last. Jonathan W. Steed (Durham University)H-Index: 69
view all 6 authors...
The incorporation of functionalised carbon nanodots within a novel low molecular weight salt hydrogel derived from 5-aminosalicylic acid is reported. The carbon dots result in markedly enhanced gelation properties, while inclusion within the hydrophobic gel results in a dramatic fluorescence enhancement for the carbon nanomaterials. The resulting hybrid CD gels exhibit a useful sensor response for heavy metal ions, particularly Pb2+.
54 CitationsSource
#1Delia López-Velázquez (BUAP: Benemérita Universidad Autónoma de Puebla)H-Index: 4
#2Armando R. Hernández-Sosa (BUAP: Benemérita Universidad Autónoma de Puebla)H-Index: 2
Last. Ernesto Pérez (CSIC: Spanish National Research Council)H-Index: 28
view all 3 authors...
Abstract We have synthesized and characterized five members of a homologous series of side chain polymers of hydroxypropyl cellulose esters obtained by homogeneous esterification with 6-[4′-(ethoxycarbonyl)biphenyl-4-yloxy]hexanoic acid. Two acylation procedures were studied. One procedure involved the acid chloride derivative and the other one was the activation of that acid with N,N′-carbonyldiimidazol. The second method yielded esters with higher degree of substitution, DS ¯ . The esters, wit...
7 CitationsSource
#1Ting-Chen Tseng (NTU: National Taiwan University)H-Index: 10
#2Lei Tao (THU: Tsinghua University)H-Index: 66
Last. Shan-hui Hsu (NTU: National Taiwan University)H-Index: 70
view all 6 authors...
: An injectable, self-healing hydrogel (≈1.5 kPa) is developed for healing nerve-system deficits. Neurosphere-like progenitors proliferate in the hydrogel and differentiate into neuron-like cells. In the zebrafish injury model, the central nervous system function is partially rescued by injection of the hydrogel and significantly rescued by injection of the neurosphere-laden hydrogel. The self-healing hydrogel may thus potentially repair the central nervous system.
249 CitationsSource
#1Fuyuan Ding (WHU: Wuhan University)H-Index: 16
#2Shuping Wu (WHU: Wuhan University)H-Index: 11
Last. Xiaowen Shi (WHU: Wuhan University)H-Index: 40
view all 10 authors...
Natural polymeric hydrogels with self-healing capability that can recover the functionalities and structures of gels after damage are extremely attractive due to their emerging applications in the biomedical field. Here we report a self-healable polymeric hydrogel by self-crosslinking two natural polymers acrylamide-modified chitin (AMC) containing amino groups and oxidized alginate containing dialdehyde groups. The generation of the self-crosslinked hydrogel relies on the dynamic covalent linka...
97 CitationsSource
#1Zhen Qi Liu (Xi'an Jiaotong University)H-Index: 5
#2Zhao Wei (Xi'an Jiaotong University)H-Index: 11
Last. Yong Mei Chen (Xi'an Jiaotong University)H-Index: 33
view all 10 authors...
Abstract Cell encapsulation in three-dimensional (3D) hydrogels can mimic native cell microenvironment and plays a major role in cell-based transplantation therapies. In this contribution, a novel in situ-forming hydrogel, Dex-l-DTT hydrogel (“l” means “linked-by”), by cross-linking glycidyl methacrylate derivatized dextran (Dex-GMA) and dithiothreitol (DTT) under physiological conditions, has been developed using thiol-Michael addition reaction. The mechanical properties, gelation process and d...
44 CitationsSource
#1Zhao Wei (Xi'an Jiaotong University)H-Index: 11
#2Jianhai Yang (Xi'an Jiaotong University)H-Index: 20
Last. Yong Mei Chen (Xi'an Jiaotong University)H-Index: 33
view all 8 authors...
A novel biocompatible polysaccharide-based self-healing hydrogel, CEC-l-OSA-l-ADH hydrogel (“l” means “linked-by”), is developed by exploiting the dynamic reaction of N-carboxyethyl chitosan (CEC) and adipic acid dihydrazide (ADH) with oxidized sodium alginate (OSA). The self-healing ability, as demonstrated by rheological recovery, macroscopic observation, and beam-shaped strain compression measurement, is attributed to the coexistence of dynamic imine and acylhydrazone bonds in the hydrogel ne...
290 CitationsSource
#1Qiang ChenH-Index: 111
#1Qiang ChenH-Index: 1
Last. Jie Zheng (University of Akron)H-Index: 66
view all 7 authors...
Double network (DN) hydrogels with two strong asymmetric networks being chemically linked have demonstrated their excellent mechanical properties as the toughest hydrogels, but chemically linked DN gels often exhibit negligible fatigue resistance and poor self-healing property due to the irreversible chain breaks in covalent-linked networks. Here, a new design strategy is proposed and demonstrated to improve both fatigue resistance and self-healing property of DN gels by introducing a ductile, n...
306 CitationsSource
#1Peng Lin (CAS: Chinese Academy of Sciences)H-Index: 7
#2Shuanhong Ma (CAS: Chinese Academy of Sciences)H-Index: 16
Last. Feng Zhou (CAS: Chinese Academy of Sciences)H-Index: 85
view all 4 authors...
A molecularly engineered dual-crosslinked hydrogel with extraordinary mechanical properties is reported. The hydrogel network is formed with both chemical crosslinking and acrylic–Fe(III) coordination; these, respectively, impart the elasticity and enhance the mechanical properties by effectively dissipating energy. The optimal hydrogel achieves a tensile stress of ca. 6 MPa at a large elongation ratio (>7 times), a toughness of 27 MJ m −3 , and a stiffness of ca. 2 MPa, and has good self-recove...
392 CitationsSource
#1Mei Xiang Wang (Xi'an Jiaotong University)H-Index: 6
#2Canhui Yang (Xi'an Jiaotong University)H-Index: 13
Last. Yong Mei Chen (Xi'an Jiaotong University)H-Index: 33
view all 8 authors...
Photoluminescent hydrogels have emerged as novel soft materials with potential applications in many fields. Although many photoluminescent hydrogels have been fabricated, their scope of usage has been severely limited by their poor mechanical performance. Here, a facile strategy is reported for preparing lanthanide (Ln)-alginate/polyacrylamide (PAAm) hydrogels with both high toughness and photoluminescence, which has been achieved by doping Ln(3+) ions (Ln = Eu, Tb, Eu/Tb) into alginate/PAAm hyd...
42 CitationsSource
Cited By29
#1Yaping Li (Haida: Hainan University)
#2Le Li (Haida: Hainan University)
Last. Lingbin Lu (Haida: Hainan University)
view all 6 authors...
Abstract Self-healing conductive hydrogels create an important class of smart skin materials with robust mechanical properties and sensitivity. Yet, these reported hydrogels cannot function steadily or be widely used because of expensive cost, complex synthetic process and weak stability. Reported here is a novel interpenetrating network hydrogel based on an all-natural strategy with carboxymethyl cellulose and dopamine as raw materials. The interpenetrating network was constructed via a facile ...
#1Haq Nawaz (BFU: Beijing Forestry University)H-Index: 1
#2Xun Zhang (BFU: Beijing Forestry University)H-Index: 13
Last. Feng Xu (BFU: Beijing Forestry University)H-Index: 96
view all 5 authors...
Abstract The progress of bio-based fluorescent smart materials and their multifunctional applications have attained increasing interest in the recent decades. Cellulose is among the cheapest and widespread raw material on earth which can be modified into diverse useful materials. This review summarizes the chemical modification of cellulose into smart fluorescent materials. This further highlights on the fabrication of the prepared fluorescent materials into films, fibers, paper strips, carbon d...
Abstract null null Hydrogel composites were prepared using polyvinyl alcohol (PVA), polyethylene oxide (PEO), and sodium carboxymethyl cellulose (NaCMC). The thermally responsive PVA/PEO/NaCMC composites exhibited self-healing at 70 °C within 20 min, which could be reduced to 15 min by adding excess PVA. Additionally, the PVA/PEO/NaCMC hydrogel displayed excellent flexibility and anti-freezing effects even at −70 ℃. The structure and morphology of the PVA/PEO/NaCMC hydrogel composites were verif...
#1Md. Saifur RahmanH-Index: 2
#1Saifur Rahman (UTEP: University of Texas at El Paso)H-Index: 4
Last. Mohammad Boshir AhmedH-Index: 19
view all 8 authors...
Carboxymethyl cellulose (CMC) is one of the most promising cellulose derivatives. Due to its characteristic surface properties, mechanical strength, tunable hydrophilicity, viscous properties, availability and abundance of raw materials, low-cost synthesis process, and likewise many contrasting aspects, it is now widely used in various advanced application fields, for example, food, paper, textile, and pharmaceutical industries, biomedical engineering, wastewater treatment, energy production, an...
ABSTRACT Carboxymethyl cellulose (CMC) is a water-soluble derivative of cellulose and a major type of cellulose ether prepared by the chemical attack of alkylating reagents on the activated non-crystalline regions of cellulose. It is the first FDA approved cellulose derivative which can be targeted for desired chemical modifications. In this review, the properties along with current advances in the physical and chemical modifications of CMC are discussed. Further, CMC and modified CMC could be e...
1 CitationsSource
#1Yue Lipei (HIT: Harbin Institute of Technology)H-Index: 5
#2Zhang Xiaoyong (HIT: Harbin Institute of Technology)H-Index: 5
Last. Yongping Bai (HIT: Harbin Institute of Technology)H-Index: 21
view all 6 authors...
Abstract Synthetic conductive materials capable of self-healing have attracted increasing attention and have been developing rapidly because of their potential applications. Despite great achievements, there is a need to advance mechanical properties and reduce the time for healing simultaneously since the branch functionalities are limited and the polymer mobilities are poor in current devices. In this work, we report an effective and simple free radical polymerization approach to synthesize hy...
#1Jiafu Shen (Hebei University)H-Index: 3
#2Ziwei Zhou (Hebei University)
Last. Jianglei Qin (Hebei University)H-Index: 9
view all 7 authors...
Abstract We report here a self-healing hydrogel with antibacterial and light-emitting properties for wound repair. The hydrogel was prepared by reaction of poly(aspartic acid) (PASP) derivatives bearing groups of quaternary ammonium and boronic acid with poly(vinyl alcohol) (PVA). Due to the dynamic nature of boronic ester bonds, bacteria-killing activity of quaternary ammonium, and light-emitting activity of phenylboronic ester, the resultant hydrogels featured self-healing, antibacterial and l...
#2Omaima M. HafezH-Index: 4
Last. Ahmed M. YoussefH-Index: 31
view all 4 authors...
#1Xinjie ZhangH-Index: 2
#2Xuechen LiangH-Index: 2
Last. Yizhen Liu (SZU: Shenzhen University)H-Index: 18
view all 6 authors...
The self-healing and self-recovery of the hydrogel materials can be promoted under sunlight without the assistance of electrical equipment by adding a light-to-heat conversion substance during the synthetic process, which will greatly extend the service life of the hydrogels even for the elastomer materials in the off-grid areas.
1 CitationsSource
#1Kum Ju Baek (KNU: Kyungpook National University)
#2Hyang Moo Lee (KNU: Kyungpook National University)H-Index: 8
Last. In Woo Cheong (KNU: Kyungpook National University)H-Index: 27
view all 10 authors...
Abstract This work describes the effect of zirconium(IV) acetylacetonate (Zr(acac)4) on the self-healing and thermomechanical properties of urethane–acrylate copolymers, and which were compared with dibutyltin dilaurate (DBTDL). For prepolymer synthesis, glyceryl methacrylate (GlyMA) and 2-hydroxyethyl methacrylate (HEMA) were chosen and copolymerized with methyl methacrylate (MMA) and butyl acrylate (BA) at a concentration of 8 mol%. The prepolymers (G8 and H8) were then crosslinked with HDI tr...