Development of autoimmune pancreatitis is independent of CDKN1A/p21-mediated pancreatic inflammation
Abstract
Objective Chronic pancreatitis (CP) and autoimmune pancreatitis (AIP) are characterised by different inflammatory processes. If pancreatic inflammation is a prerequisite for autoimmunity is still unclear. AIP is considered mostly a T cell-mediated disease; however, in induction of CP, macrophages play a pivotal role. p21—a member of cyclin-dependent kinase inhibitors—can influence inflammatory processes, in particular can regulate T cell...
Paper Details
Title
Development of autoimmune pancreatitis is independent of CDKN1A/p21-mediated pancreatic inflammation
Published Date
Aug 3, 2017
Journal
Volume
67
Issue
9
Pages
1663 - 1673
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