DNA demethylation pattern of in-vitro fertilized and cloned porcine pronuclear stage embryos
Abstract
Recent studies in mice showed that the Ten-eleven translocation Enzymes (TET) family is involved in the active DNA demethylation. The isotype TET-3 is responsible for the conversion of 5mc (5-methylcytosine) to 5hmc (5-hydroxymethylcytosine) at the pronuclear stages of mouse embryo. This study was performed to investigate the pattern of methylation change and the role of TET family in the demethylation process of porcine in-vitro fertilization...
Paper Details
Title
DNA demethylation pattern of in-vitro fertilized and cloned porcine pronuclear stage embryos
Published Date
Oct 1, 2017
Journal
Volume
473
Pages
45 - 50
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