Abstract 5452: Antitumor activity of miR-34a in peritoneal mesothelioma relies on c-MET and AXL inhibition: Persistent activation of ERK and AKT signaling as a possible cytoprotective mechanism

The value of microRNAs (miRNAs) as novel targets for cancer therapy is now widely recognized. However, no information is currently available on the expression/functional role of miRNAs in diffuse malignant peritoneal mesothelioma (DMPM), a rapidly lethal disease, poorly responsive to conventional treatments, for which the development of new therapeutic strategies is urgently needed. Here, we evaluated the expression and biological effects of...