Histone demethylase PHF8 accelerates the progression of colorectal cancer and can be regulated by miR-488 in vitro
Abstract
Plant homeo domain finger protein 8 (PHF8), as an oncogene, has been highlighted in cancer development and progression. However, its clinical significance and underlying molecular mechanisms in colorectal cancer (CRC) remain to be fully elucidated. In the present study, the role of PHF8 in the progression of CRC was investigated. The mRNA and protein levels of PHF8 in tissues from patients with CRC and cell lines were detected using the reverse...
Paper Details
Title
Histone demethylase PHF8 accelerates the progression of colorectal cancer and can be regulated by miR-488 in vitro
Published Date
Aug 1, 2017
Journal
Volume
16
Issue
4
Pages
4437 - 4444
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